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Human Sperm Gene Is 600 Million Years Old,


Still Waters

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Just as styles in sexy clothes or fashion change from year to year and culture to culture, "sexy" genes, or genes specific to sex, also change rapidly. But there is one sex-specific gene so vital, its function has remained unaltered throughout evolution and is found in almost all animals, according to new research from Northwestern University Feinberg School of Medicine.

The gene, called Boule, is responsible for sperm production. Northwestern scientists also discovered in their research that Boule appears to be the only gene known to be exclusively required for sperm production from an insect to a mammal.

"This is the first clear evidence that suggests our ability to produce sperm is very ancient, probably originating at the dawn of animal evolution 600 million years ago," said Eugene Xu, assistant professor of obstetrics and gynecology at Feinberg. "This finding suggests that all animal sperm production likely comes from a common prototype."

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