QUOTE(Regency @ Aug 13 2007, 06:55 AM)

On a different angle, there's much talk here in the UK about the MMR vaccine and autism.
I can only speak as I find and my son, who now is profoundly autistic - can't speak a word and is still in nappies at 7, could respond and speak BEFORE his MMR and I have home video to prove this. We have him waving when asked to and clapping, calling his brother's name, singing and he had fantastic eye contact. He couldn't wave or clap if I asked him to now. He regressed quickly after the MMR but the medical response to this is that autism is a regressive condition in some cases. However, his consultant doesn't dismiss the MMR debate.
The debate about the MMR rages here in the UK.
Sorry to use you as an example, But this is a perfect example of just how long it takes information to filter down through science to society. A shame really. I had this argument a couple of years ago with my wife (who spent 2 years in medical school only to switch to a Ph.D. program). Anyway, rather than do the research herself, which she is quite capable of doing, she simply conformed to public opinion. So heres a help withe the research for anyone that thinks MMR and Autism share a correlation.
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This study provides three strong arguments against a causal relation between MMR vaccination and autism. First, the risk of autism was similar in vaccinated and unvaccinated children, in both age-adjusted and fully adjusted analyses. Second, there was no temporal clustering of cases of autism at any time after immunization. Third, neither autistic disorder nor other autistic-spectrum disorders were associated with MMR vaccination.
Madsen , K. M., A.Hviid, M. Vestergaard , and D. Schendel . " A Population-Based Study of Measles, Mumps, and Rubella Vaccination and Autism."
New England Journal of Medicine. 347(2002): 1477-1482.
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There is uncertainty about whether the prevalence of autism is increasing. 18 Our study is consistent with an increase in the incidence of autism in recent birth cohorts. This increase may be real or a reflection of other factors such as better recording arrangements in recent years, the increasing recognition of higher functioning children with autism and Asperger's syndrome, together with an increasing number of professionals trained to recognise the disorders. However, whether real or artifactual, the trend in increasing incidence with successive birth cohorts to 1992 was not related to the introduction of MMR vaccine or to vaccine coverage, which reached a plateau during a period in which autism incidence was apparently increasing.
Taylor, Brent , Elizabeth Miller, CPaddy Farrington, and Maria-Christina Petropoulos. "Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association." The Lancet. 353(1999): 2026-2029.
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Because the incidence of autism among 2 to 5 year olds increased markedly among boys born in each year separately from 1988 to 1993 while MMR vaccine coverage was over 95% for successive annual birth cohorts, the data provide evidence that no correlation exists between the prevalence of MMR vaccination and the rapid increase in the risk of autism over time. The explanation for the marked increase in risk of the diagnosis of autism in the past decade remains uncertain.
Kaye JA, del Mar Melero-Montes M, Jick H. Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners:a time trend analysis. BMJ 2001;322:460-3.
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These data do not suggest an association between MMR immunization among young children and an increase in autism occurrence.
Dales L, Hammer SJ, Smith NJ. Time trends in autism and in MMR immunization coverage in California. JAMA 2001;285:1183-5.
Not sure if posting this much is abusing my access to NEJM but its well written and should be available for more than just scientists to read.
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A report in this issue of the Journal (pages 1477–1482) provides an objective analysis of the rates of autism in relation to MMR-vaccination status in a well-defined population of more than half a million children in Denmark, about one fifth of whom had not received the MMR vaccine. This careful and convincing study shows that there is no association between autism and MMR vaccination. Other studies have also found no such association.
Unfortunately, objective data are not likely to put an end to the controversy. Strongly held beliefs are difficult to change. We live in an era in which the public does not have a high degree of trust in the vaccine manufacturers, the government, or the medical establishment. Consumers have become highly sensitive about safety, and their confidence has not been bolstered by recent recalls of approved drugs or by controversies such as that over mercury-containing preservatives in vaccines (thimerosal, which has now been removed). The large number of approved vaccines and the laws that require vaccination for school entry only increase the tension. Some anti-vaccine groups have received wide publicity, and they try to convince worried parents that avoiding vaccination is "playing it safe." Internet sites are filled with accusations about damage from the MMR vaccine and other vaccines. Some parents tell moving stories about their children who showed the first signs of autism in the months after vaccination. Such experiences have already led to congressional hearings. But however painful these stories may be, anecdotes are not proof. The association of autism with MMR vaccination appears to be only a predictable coincidence, since nearly 90 percent of children in this country receive the MMR vaccine at about 15 months of age.
Unsubstantiated accusations that a vaccine causes harm can have serious consequences. Some people begin to avoid vaccination, increasing the number at risk, particularly in communities where anti-vaccine activists are most successful. Once a vaccine has been tied repeatedly to even an unsupported claim of an adverse effect, costly legal action usually follows, even if the vaccine is eventually proved to be safe. The companies that produce vaccines come to associate vaccines with adverse economic effects for themselves, with little profit and huge liability. Effective vaccines may be withdrawn from the market. It becomes harder to run vaccination programs, including those in developing countries where the needs are greatest.
Those arguing against vaccination forget how bad the illnesses and their complications can be. They forget that in this country before the development of the measles vaccine, thousands of children had severe illness from measles, sometimes resulting in permanent disability. In 1960, 400 children died from measles. But the biggest tragedy is that outside of the developed countries, more than a million children still die from this disease each year. Those deaths are preventable by a measles vaccine that is cost effective and safe. Children everywhere deserve the protection that carefully developed, carefully monitored vaccines can provide against so much disease.
Campion EW. Suspicions about the safety of vaccines. N Engl J Med. 2002;347 :1474 –1475