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A new study is trying to establish the intrinsic vibration modes of capsids---the protein shells of virus particles that package its genetic material---with a view toward rupturing them and thereby killing the pathogenic virus. If the capsid resonant frequencies could be determined, then possibly light or sound waves might be used to shatter the capsids the way the opera singer Enrico Caruso supposedly shattered wine glasses by sustaining a note at exactly the resonant frequency of the glass. This approach to attacking viruses is alternative to treating them with chemicals, which is not always effective; furthermore, the chemicals can do damage to healthy cells, or the viruses can mutate and defeat chemical defenses. Hence the importance of attempting to undo viruses with mechanical means.
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New Way to Kill Viruses: Shake Them to Death
http://www.livescience.com/health/080205-v...shattering.html
By Michael Schirber, Special to LiveScience
One challenge is that laser light cannot penetrate the skin very deeply. But Sankey imagines that a patient might be hooked up to a dialysis-like machine that cycles blood through a tube where it can be hit with a laser. Or perhaps, ultrasound can be used instead of lasers.
These treatments would presumably be safer for patients than many antiviral drugs that can have terrible side-effects. Normal cells should not be affected by the virus-killing lasers or sound waves because they have resonant frequencies much lower than those of viruses, Sankey said.
http://www.livescience.com/health/080205-v...shattering.html
By Michael Schirber, Special to LiveScience
One challenge is that laser light cannot penetrate the skin very deeply. But Sankey imagines that a patient might be hooked up to a dialysis-like machine that cycles blood through a tube where it can be hit with a laser. Or perhaps, ultrasound can be used instead of lasers.
These treatments would presumably be safer for patients than many antiviral drugs that can have terrible side-effects. Normal cells should not be affected by the virus-killing lasers or sound waves because they have resonant frequencies much lower than those of viruses, Sankey said.
