Surgeons have separated two-year-old Egyptian twins joined at the head in a painstaking operation at a Dallas, Texas, hospital.
The operation on Mohamed and Ahmed Ibrahim, who have separate brains but share an important vein, began on Saturday and may last until Monday.
The boys faced a lifetime of medical problems if they remained connected.
The last such operation resulted in the deaths of adult Iranian twins in July but their father said he had no option.
Conjoined at the crown of the head, the boys have had trouble closing their eyes, moving their necks and swallowing.
On Sunday, surgeons at the Children's Medical Center in Dallas completed the most difficult and dangerous part of the procedure: separating the shared brain material and the shared circulatory systems which feed bloods to their brains.
"If there are no major complications, the operation should end on Sunday," said hospital spokesman Dr Jim Thomas.
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