Help - Search - Members - Calendar
Full Version: Treatment to neutralise all flu
Unexplained Mysteries Discussion Forums > Science > Natural World
Raptor
Treatment 'to neutralise all flu'


Scientists say they are developing an entirely new way of providing instant protection against flu.
In preliminary tests, it was found to protect animals against various strains of the virus - and may also protect against future pandemic strains.

University of Warwick researchers used a flu virus naturally stripped of some genetic material to compete with other invading flu viruses.

This slowed the rate of infection so much the body could fight it off.

In effect, the invading virus became its own vaccine by triggering an immune response sufficiently powerful to neutralise it before it could gain a strong enough foothold.

The Warwick team plan to develop the treatment as a nasal spray.

Experts warned much more testing was required.

However, they said the development of the vaccine was timely, amid concerns the H5N1 bird flu strain circulating in south east Asia could mutate into a pandemic strain which would put millions of lives at risk.

...

Professor Nigel Dimmock has spent more than two decades developing the new approach.

The "protecting virus" with which he worked had naturally lost around 80% of the genetic material of one of its eight RNA constituent segments. This deletion makes the virus harmless and prevents it from reproducing by itself within a cell, so that it cannot spread like a normal influenza virus.

However, if it is joined in the cell by another influenza virus, it retains its harmless nature but starts to reproduce - and at a much faster rate than the new influenza virus.

This fast reproduction rate - spurred by the new flu infection - means that the new invading influenza is effectively crowded out.

This vastly slows the progress of the new infection, prevents flu symptoms, and gives the body time to develop an immune response to the harmful new invader.





Source

\__ _ _ _ _ ___/\__ _ _ _ _ ___/\__ _ _ _ _ ___/\__ _ _ _ _ ___/



Looks hopeful. yes.gif
frogfish
QUOTE
This fast reproduction rate - spurred by the new flu infection - means that the new invading influenza is effectively crowded out.

This vastly slows the progress of the new infection, prevents flu symptoms, and gives the body time to develop an immune response to the harmful new invader.

Ingenious idea, especially since the immune system is the only way to kill of a flu virus.

It sounds hopeful.
Samael
A flu cure? Why was I not informed? original.gif

This is a good thing, though. Flu is much more deadly than people think. Look at what happened after WW1. And what happened to the Aztecs and Incas.
frogfish
It's not a cure yet...It is still in the research phase.
Samael
QUOTE(frogfish @ Oct 15 2006, 10:33 PM) [snapback]1391002[/snapback]

It's not a cure yet...It is still in the research phase.


disgust.gif You know what I mean.
Goblin-5
Hmmmmmm.... if it has lost 80% of one of its constitutive segments it was probably the reproductive region... especially if complementation with another virus causes it to regain its activity. I think there is more to this than is in the article. We routinely use attenuated viruses in the lab and those have a couple of deletions which have to be added in for the virus to replicate. I would like to know what strain of flu virus it was originally and just what was knocked out and how
RollingThunder06
Worth keeping updated on. I know there is still a lot of information needed but it does sound like they are on the right track.
whoa182
This should be effective for us too... it seems like we are turning a corner where far better treatments are coming along to not just deal with symptoms anymore, but very intelligent approaches to dealing with common problems.

Viridis
QUOTE(Goblin-5 @ Oct 18 2006, 06:10 PM) [snapback]1395300[/snapback]

Hmmmmmm.... if it has lost 80% of one of its constitutive segments it was probably the reproductive region... especially if complementation with another virus causes it to regain its activity.



"This deletion makes the virus harmless and prevents it from reproducing by itself within a cell"

I would assume from that sentence that a lot of the deleted part was the part that causes flu symptoms...
This is a "lo-fi" version of our main content. To view the full version with more information, formatting and images, please click here.
Invision Power Board © 2001-2008 Invision Power Services, Inc.