http://www.csiro.au/pubgenesite/research/h...on/frogGlue.htm
"Scientists at CSIRO Molecular Science are hoping to develop new surgical adhesives by studying a natural glue that comes from frogs.
Australian frogs of the genus Notaden secrete a sticky exudate when provoked. This sets rapidly into a tacky elastic solid that adheres tightly to a wide range of materials, even in wet conditions. Scientists are aiming to mimic the design of this natural material ('Frog Glue') to produce a medical adhesive.
The research is being co-developed by CSIRO Molecular Science and the University of Adelaide. The goal is to understand the mechanism by which the frog material functions as a biological adhesive, and to use this knowledge in developing novel bonding agents that are adhesive, flexible, strong, non-toxic, and biocompatible.............."
http://www.abc.net.au/catalyst/stories/s1705318.htm
Full Version: Frog Glue
Reconstructed joints
In the sheep experiment, orthopaedic surgeon George Murrell of the University of New South Wales made a tear in the meniscal knee cartilage of ten sheep, treated each with frog glue, and reconstructed the joints.
Ten weeks later, Tyler and Murrell examined the sheep’s knees. The frog glue had held the cut fragments together, and collagen, the main component of cartilage, had filled the gap.
Tyler and colleagues - including John Ramshaw of the Commonwealth Scientific and Industrial Research Organisation in Melbourne - have also shown that the frog glue will stick plastics, wood, glass, metal and Teflon. It is strong even in moist conditions.
The set glue is also flexible and has a porous structure that should make it permeable to gas, nutrients and possibly even cells, which would encourage healing.
Ramshaw and his colleagues have also characterised a key component of the glue, a novel protein unrelated to other biological adhesives such as those used to stick barnacles to surfaces. They are now developing a genetically engineered version of that protein.
The findings were presented on 28 September at ComBio2004, a biological science meeting in Perth.
http://www.newscientist.com/article.ns?id=dn6492
Reconstructed joints
In the sheep experiment, orthopaedic surgeon George Murrell of the University of New South Wales made a tear in the meniscal knee cartilage of ten sheep, treated each with frog glue, and reconstructed the joints.
Ten weeks later, Tyler and Murrell examined the sheep’s knees. The frog glue had held the cut fragments together, and collagen, the main component of cartilage, had filled the gap.
Tyler and colleagues - including John Ramshaw of the Commonwealth Scientific and Industrial Research Organisation in Melbourne - have also shown that the frog glue will stick plastics, wood, glass, metal and Teflon. It is strong even in moist conditions.
The set glue is also flexible and has a porous structure that should make it permeable to gas, nutrients and possibly even cells, which would encourage healing.
Ramshaw and his colleagues have also characterised a key component of the glue, a novel protein unrelated to other biological adhesives such as those used to stick barnacles to surfaces. They are now developing a genetically engineered version of that protein.
The findings were presented on 28 September at ComBio2004, a biological science meeting in Perth.
In the sheep experiment, orthopaedic surgeon George Murrell of the University of New South Wales made a tear in the meniscal knee cartilage of ten sheep, treated each with frog glue, and reconstructed the joints.
Ten weeks later, Tyler and Murrell examined the sheep’s knees. The frog glue had held the cut fragments together, and collagen, the main component of cartilage, had filled the gap.
Tyler and colleagues - including John Ramshaw of the Commonwealth Scientific and Industrial Research Organisation in Melbourne - have also shown that the frog glue will stick plastics, wood, glass, metal and Teflon. It is strong even in moist conditions.
The set glue is also flexible and has a porous structure that should make it permeable to gas, nutrients and possibly even cells, which would encourage healing.
Ramshaw and his colleagues have also characterised a key component of the glue, a novel protein unrelated to other biological adhesives such as those used to stick barnacles to surfaces. They are now developing a genetically engineered version of that protein.
The findings were presented on 28 September at ComBio2004, a biological science meeting in Perth.
http://www.newscientist.com/article.ns?id=dn6492
Reconstructed joints
In the sheep experiment, orthopaedic surgeon George Murrell of the University of New South Wales made a tear in the meniscal knee cartilage of ten sheep, treated each with frog glue, and reconstructed the joints.
Ten weeks later, Tyler and Murrell examined the sheep’s knees. The frog glue had held the cut fragments together, and collagen, the main component of cartilage, had filled the gap.
Tyler and colleagues - including John Ramshaw of the Commonwealth Scientific and Industrial Research Organisation in Melbourne - have also shown that the frog glue will stick plastics, wood, glass, metal and Teflon. It is strong even in moist conditions.
The set glue is also flexible and has a porous structure that should make it permeable to gas, nutrients and possibly even cells, which would encourage healing.
Ramshaw and his colleagues have also characterised a key component of the glue, a novel protein unrelated to other biological adhesives such as those used to stick barnacles to surfaces. They are now developing a genetically engineered version of that protein.
The findings were presented on 28 September at ComBio2004, a biological science meeting in Perth.
http://www.environment.gov.au/soe/2006/pub...rogs/index.html
A recent threat is a fungal disease called chytridiomycosis (generally referred to as chytrid for short). The fungus invades the skin and, because frogs rely upon the skin for respiration, infected ones become lethargic and then die. At present there is no known cure.
The extinction of any animal or plant species is an irreversible tragedy, but the loss of frogs is particularly disturbing. The reason for this is that complex glands in frog skin secrete a wide variety of chemical compounds of benefit to human and animal medicine. These compounds include novel antibiotics, mosquito repellents, and even a glue which is being tested for its use in surgery. Much of this work is being undertaken in Australia and does not require a single frog to be killed. If frog species disappear, the opportunity to search for other new secretions will disappear as well.
Another reason for concern is the fact that frogs are providing an early warning of pollution, and it is important to take notice.
A recent threat is a fungal disease called chytridiomycosis (generally referred to as chytrid for short). The fungus invades the skin and, because frogs rely upon the skin for respiration, infected ones become lethargic and then die. At present there is no known cure.
The extinction of any animal or plant species is an irreversible tragedy, but the loss of frogs is particularly disturbing. The reason for this is that complex glands in frog skin secrete a wide variety of chemical compounds of benefit to human and animal medicine. These compounds include novel antibiotics, mosquito repellents, and even a glue which is being tested for its use in surgery. Much of this work is being undertaken in Australia and does not require a single frog to be killed. If frog species disappear, the opportunity to search for other new secretions will disappear as well.
Another reason for concern is the fact that frogs are providing an early warning of pollution, and it is important to take notice.
.... ????????????If we are treated with frog products.... eg ...the frog glue...and it's proteins get absorbed with ours... would we to be in danger of catching this new frog fungus that is slowly destroying the amphibean population????????
QUOTE
If we are treated with frog products.... eg ...the frog glue...and it's proteins get absorbed with ours... would we to be in danger of catching this new frog fungus that is slowly destroying the amphibean population????????
No
QUOTE(frogfish @ Feb 21 2007, 06:10 AM) [snapback]1551403[/snapback]
No
sure???
Yes, I'm sure 
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