A part of the brain responsible for aging could offer a new way to manipulate the aging process.
Scientists at the Albert Einstein School of Medicine found that by manipulating this region in mice they were able to extend the animals' lifespan by up to 20%. The method involves NF-κB, a molecule that controls DNA transcription and becomes more active with age. Injecting the mice with an NF-κB inhibitor resulted in a slowing of the aging process while the use of a stimulant had the opposite effect.
"They also showed less age-related decline in muscle strength, skin thickness, bone mass, and tail-tendon integrity," the team reported. Molecular biologist David Sinclair has hailed the discovery as a major breakthrough in anti-aging research.
"Scientists at the Albert Einstein School of Medicine say they’ve discovered a brain region that may control aging throughout the entire body."
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Source: Business Week
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