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Eldorado

An alternate theory for Alzheimer's causes

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Eldorado

"Alzheimer's disease, the most common cause of dementia among the elderly, is characterized by plaques and tangles in the brain, with most efforts at finding a cure focused on these abnormal structures. But a University of California, Riverside, research team has identified alternate chemistry that could account for the various pathologies associated with the disease."

Full report at Science Daily: https://www.sciencedaily.com/releases/2019/08/190812144930.htm

 

“In addition to plaques, lysosomal storage is observed in brains of people who have Alzheimer’s disease. Neurons — fragile cells that do not undergo cell division — are susceptible to lysosomal problems, specifically, lysosomal storage, which we report is a likely cause of Alzheimer’s disease.”

At the Uni of California, Riverside,: https://news.ucr.edu/articles/2019/08/12/alternate-theory-what-causes-alzheimers-disease

 

"Spontaneous Isomerization of Long-Lived Proteins Provides a Molecular Mechanism for the Lysosomal Failure Observed in Alzheimer’s Disease"

Paper at ACS Publications: https://pubs.acs.org/doi/10.1021/acscentsci.9b00369

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