Can Anti-Malarial Drug Treat Corona Virus?

[kartikg]

Any data coming out about the efficacy of chloroquine in New York hospitals? 

[Helen of Annoy]

13 minutes ago, kartikg said:

Any data coming out about the efficacy of chloroquine in New York hospitals? 

Not yet, but the results with COVID will more than likely be very similar to those with other viruses. 

It was more than irresponsible to claim anti-malarics are the 'gamechanger' or whatnot. 

 

 https://www.theguardian.com/science/2020/mar/25/can-chloroquine-really-help-treat-coronavirus-patients

“Researchers have tried this drug on virus after virus, and it never works out in humans. The dose needed is just too high,” Susanne Herold, an expert on pulmonary infections at the University of Giessen, recently told Science magazine.

 

[+susieice]

On 3/31/2020 at 4:57 AM, kartikg said:

Any data coming out about the efficacy of chloroquine in New York hospitals? 

New Jersey is reporting a success story.

https://www.nj.com/opinion/2020/03/covid-19-patient-successfully-treated-with-unproven-drug-in-nj-is-a-ray-hope-opinion.html?utm_source=facebook&utm_content=nj_facebook_njcom&utm_campaign=njcom_sf&utm_medium=social&fbclid=IwAR0o2MsgCZlr2sAnySb7BDSAqS706lPEvsg9w3WpDAw3ainCmNBSfuigJKI

[Katniss]

 

I think the problem is there is not enough to go around and that is why some people are downplaying it's potential. And to stop hoarding.

Edited April 2, 2020 by Katniss

[Katniss]

Testimonies from patients and doctors opinions.

 

[+susieice]

Michigan is reporting some success in managing the virus with hydroxychloroquine but doesn't see it as a miracle cure. It's not the medication to actually fight it.

https://www.mlive.com/public-interest/2020/03/michigan-hospital-reports-some-success-using-experimental-coronavirus-treatment.html?utm_campaign=flintjournal_sf&utm_medium=social&utm_source=facebook&fbclid=IwAR3RVa2oUFIiu6rhSICLtu445YRLpXF86FTImdZD0QGkeVL-TY7-tYpZcXU

[stevewinn]

There doesn't seem to be a treatment except for supportive. mechanically or chemically I know in the UK when they scan for the virus if they also find a bacterial infection they treat for that also to assist the persons immune system in fighting or concentrating on corona.

im sure if the Malaria-drugs were of any use we'd have seen them in use and referenced in the govt/health expert briefings.  

according to worldometer for stats a lot of people on this site are using it. - It shows 99% in mild condition. and a very small number 1% in serious or critical condition in also shows people who find themselves in serious / critical bracket then recovery chances are 5%. 

[Helen of Annoy]

Chinese scientists have useful anti-bodies. In other words, no vaccine yet, or 'miracle' cure, but this could make a difference, unlike Trump's childish, irresponsible, used-car-salesman blathering about gifts of god.  

https://www.reuters.com/article/us-health-coronavirus-china-scientists/chinese-scientists-seeking-potential-covid-19-treatment-find-effective-antibodies-idUSKBN21J4QW

A team of Chinese scientists has isolated several antibodies that it says are “extremely effective” at blocking the ability of the new coronavirus to enter cells, which eventually could be helpful in treating or preventing COVID-19.

[Raptor Witness]

Finally the President mentions zinc with Hyroxychloroquine. Good job ....

 

[Tatetopa]

On 3/24/2020 at 2:23 PM, hacktorp said:

Believe me, if Trump tells people they must stay hydrated, SOMEBODY will run to the nearest toilet and gulp down several gallons.

Then they will blame Trump because they don't feel well.

The first part is no doubt true, most likely to be practiced by his supporters.  The second part I doubt.  They would blame Obama or Clinton.

[Tatetopa]

OK, the President wants to be a cheerleader and help Americans that is good.  

He could stick to the fields he is expert in though.  

People are worried about the economy, their jobs, their 401k's, international trade, plans for tariffs, when the aid is coming, of employees and businesses.what categories will get help   He knows a lot about those topics.  That would let people know there is a plan.

He could have offered financial advice for this time of uncertainty.

He has a medical task force.  He could of as the old saying goes, "Leave medicine to doctors."

[+and-then]

2 hours ago, Tatetopa said:

He could have offered financial advice for this time of uncertainty.

He already is doing that.  He's trying to give some hope to those who need it most.  The dying and their families.  If the hate Trump brigade would let it feckin' GO for just a little while, we might all feel better.  I'm getting to the point of wanting to spit it someone's face over this constant, childish nagging.

[Raptor Witness]

13 minutes ago, and then said:

He already is doing that.  He's trying to give some hope to those who need it most.  The dying and their families.  If the hate Trump brigade would let it feckin' GO for just a little while, we might all feel better.  I'm getting to the point of wanting to spit it someone's face over this constant, childish nagging.

Please take your temperature, first. 

 

[odas]

59 minutes ago, Raptor Witness said:

Please take your temperature, first. 

 

It would still be a firm NO for me.

[Tatetopa]

1 hour ago, and then said:

He already is doing that.  He's trying to give some hope to those who need it most.  The dying and their families.  If the hate Trump brigade would let it feckin' GO for just a little while, we might all feel better.  I'm getting to the point of wanting to spit it someone's face over this constant, childish nagging.

It just seems natural and a way to avoid some of the press briefing acrimony to  speak about what 80% of us who do not get the virus, and 98% of us who do not die will need to know.  Admittedly nobody in the press is asking about it either.

What is the best course of action for those with 401k's?   How will this affect any trade deals we were going to make with China?  Are Chinese products safe to import?  What plans are we going to make to bring industry back to America? Are we going to invest heavily in infrastructure?

You have certainly been vocal about this too.  Wouldn't you like to hear what the president intends to do?  Isn't that also a vital part of dealing with covid19?

[+susieice]

Another possibility?

https://www.webmd.com/lung/news/20200407/parasite-drug-shows-early-promise-against-covid-19?fbclid=IwAR0TCf78aoY-eG5ASc3807WjpkTteJsLP5WKmQ9DZ5sLQsrFAJ3-dUtb-Sk

[aztek]

interesting article.

https://www.yahoo.com/news/fine-flailing-rapid-declines-covid-203026098.html

 

Quote

 

One medical worker called it "insane," another said it induces paranoia - the speed with which patients are declining and dying from the novel coronavirus is shocking even veteran doctors and nurses as they scramble to determine how to stop such sudden deterioration.

Patients "look fine, feel fine, then you turn around and they're unresponsive," said Diana Torres, a nurse at Mount Sinai Hospital in New York, It isn’t just elderly or patients with underlying health conditions who can be fine one minute and at death's door the next. It can happen for the young and healthy, too, Patients might enter the hospital with strong oxygen levels and be engaged in happy conversation, said a resident emergency doctor at New York-Presbyterian Hospital, only to be "gasping for breath" and intubated a few hours later.

 

The quick turns for the worse are likely products of an "overly exuberant" reaction by the immune system as it fights the virus, said Dr. Otto Yang, an infectious disease specialist at the UCLA Medical Center in Los Angeles.Called a cytokine storm, it occurs when the body overproduces immune cells and their activating compounds - cytokines - causing dangerously high blood pressure, lung damage and organ failure.

 

so bp goes up dangerously high and quick, and they are given pressurized oxygen, which induces spasms, yea, no wonder their organs fail.  i wonder what autopsy shows, but i heard they are not doing them now due to risk of infection.  

 

Edited April 9, 2020 by aztek

[aztek]

Some doctors moving away from ventilators for virus patients

 

Quote

 

Generally speaking, 40% to 50% of patients with severe respiratory distress die while on ventilators, experts say. But 80% or more of coronavirus patients placed on the machines in New York City have died, state and city officials say.

But some health professionals have wondered whether ventilators might actually make matters worse in certain patients, perhaps by igniting or worsening a harmful immune system reaction.

That's speculation. But experts do say ventilators can be damaging to a patient over time, as high-pressure oxygen is forced into the tiny air sacs in a patient's lungs.

But increasingly, physicians are trying other measures first. One is having patients lie in different positions — including on their stomachs — to allow different parts of the lung to aerate better. Another is giving patients more oxygen through nose tubes or other devices. Some doctors are experimenting with adding nitric oxide to the mix, to help improve blood flow and oxygen to the least damaged parts of the lungs.

 

https://www.yahoo.com/lifestyle/doctors-moving-away-ventilators-virus-185207787.html

[Tatetopa]

Anybody have any information about steroids like prednisone used to reduce inflammation?  it was given to me along with antibiotics when I had pneumonia.

[+susieice]

Some doctors are moving away from using ventilators.

https://www.usnews.com/news/world/articles/2020-04-08/some-doctors-moving-away-from-ventilators-for-virus-patients

Edited April 9, 2020 by susieice

[+susieice]

1 hour ago, Tatetopa said:

Anybody have any information about steroids like prednisone used to reduce inflammation?  it was given to me along with antibiotics when I had pneumonia.

Right now it seems that WHO doesn't recommend the use of steroids.

https://www.medicalnewstoday.com/articles/people-on-steroids-for-chronic-illness-may-be-more-at-risk-of-covid-19

https://www.sciencedaily.com/releases/2020/02/200206110703.htm

[kartikg]

I read that hcq should be started in very early stages of infection rather than waiting for the patients to get too sick. 

[aztek]

6 hours ago, susieice said:

Right now it seems that WHO doesn't recommend the use of steroids.

https://www.medicalnewstoday.com/articles/people-on-steroids-for-chronic-illness-may-be-more-at-risk-of-covid-19

https://www.sciencedaily.com/releases/2020/02/200206110703.htm

trump is right to trash WHO, let doctors on the spot decide based on patient history and individual approach, what is appropriate, not some bureaucrat who prbly knows next to nothing and has his own agenda,   i do not see their recommendations work out too well, 

[odas]

I am reading now in balkan newspapers that the reason why ex comunist countries have a smaller covid 19 case amonunt could be because of the mandatory typhus vacine after WWII. 

[Raptor Witness]

17 hours ago, Tatetopa said:

Anybody have any information about steroids like prednisone used to reduce inflammation?  it was given to me along with antibiotics when I had pneumonia.

I think it’s a problem when you’re dealing with any type of viral infection, because prednisone typically dampens the immune response. On the one hand it might prevent too much inflammation in the lungs, caused by a cytokine storm, but it may also act prevent your body from fighting off the virus. 

This is a question for a medical doctor, but from what I’ve casually read, they are not using steroids to prevent cytokine storms.