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Discovery of new cellular rhythm in the heart shows how it tracks the 24-hour cycle


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Posted (IP: Staff) ·

Scientists have identified a new cellular mechanism that helps the mammal heart stay in sync with circadian rhythms, and the discovery could help identify why some are at greater risk of cardiac problems.

Circadian rhythms are processes that help to regulate time-based systems in the body around a roughly 24-hour cycle, affecting sleeping and waking, how our metabolism functions, and our cognitive processes too.

It's been known for a long time that the heart is subject to this biological clock, with people showing an elevated heart rate in the morning, and a much lower rate while we sleep at night.

Just how the heart facilitates making these changes throughout the day is still something of a mystery, however. Part of the explanation is signals relayed from the nervous system, but a new discovery made by scientists at the MRC Laboratory for Molecular Biology at the University of Cambridge goes some way to explaining how the heart also independently shifts gears at the cellular level.

https://www.sciencealert.com/even-our-hearts-beat-to-circadian-rhythms-and-this-new-discovery-helps-explain-how

https://www.nature.com/articles/s41467-021-25942-4

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