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Impact of SARS-CoV-2 Epidemic on Antimicrobial Resistance: A Literature Review

Manwon Lender

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This is a new threat to those treated in medical facilities for COVID 19, apparently the medical facilities that are main locations for the treatment of COVID 19 are having abnormally high increases in drug resistance pathogens. In many cases these pathogens are the cause of drug resistant forms of Pneumonia that are creating deadly complications for hospitalized COVID 19 patients. These drug resistant pathogens have grown on a large scale since the beginning of this Pandemic and only now has enough research data been compiled to see this deadly trend. 

SARS-CoV2 pandemic lead to a massive disruption of healthcare systems at all levels. In acute and intensive care settings, inappropriate antimicrobial exposure, and discontinuation of infection control measures may drive selection and diffusion of drug-resistant pathogens. In COVID-19 settings, microorganisms that pose particular risk of nosocomial outbreaks are carbapenem-resistant A. baumannii, methicillin-resistant S. aureus, carbapenem-resistant K. pneumoniae, and C. auris. 

In conclusion, based on the literature review, we identified an urgent need of high-quality, controlled, perspective studies addressing the issue of antibiotic resistance in COVID-19 settings, with special focus on COVID-19 ICUs that may be new drivers of AMR selection. Novel approaches to stewardship must adapt to COVID-19 settings and local epidemiology and, most importantly, a new focus on adherence to IPC measures is urgently needed. Antimicrobial resistance will continue to pose a substantial threat to healthcare systems for the years to come. To mitigate the potential long-term impact of COVID-19 on AMR, it is necessary to integrate antimicrobial stewardship activities in the pandemic response.



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The extra level of sanitization has led the other known pathogens to become super-pathogens that are now resistant to hand sanitizers and antibiotics? I have heard this warning for decades, that antibacterial soap would make the bacteria resistant. If you don't completely kill the disease it is just going to bounce back and come for revenge.

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