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How long have is been known that COVID-19 is dangerous


stereologist

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Just now, OpenMindedSceptic said:

Millions dead "of" covid?

Are you really sure of this? 

This is going to be good. 

Millions dead of COVID-19. Ten of millions injured by the disease

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https://pratt.duke.edu/about/news/covid-19-can-directly-infect-and-damage-human-kidney-cells

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The virus that causes COVID-19, SARS-CoV-2, can directly infect a specialized type of kidney cell. The discovery helps explain why acute kidney injury is one of the main complications observed in patients with severe COVID-19, according to biomedical engineers and virologists at Duke University.

The research appeared online April 20 in the journal Frontiers in Cell and Developmental Biology.

The mechanisms of the dangers of COVID-19 are being explored and some answers are being worked out.

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From the previous link

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The issue came to Samira Musah’s attention when she attended a virtual symposium in the spring of 2020. Musah, an assistant professor of biomedical engineering and medicine at Duke, listened as physicians presented research that described how patients who had never experienced any kidney-related issues were developing kidney disease after getting sick with COVID-19.

“It was shocking to hear doctors describe how patients who were healthy suddenly developed kidney injury and needed to go on dialysis after contracting SARS-CoV-2,” said Musah. “It was clear that the virus was doing something to the kidneys, but it was so early in the pandemic that nobody was sure what was going on.”

Again we see that the dangers were known over 2 years ago.

People continue to pretend that COVID-19 kills or you walk unscathed. That is false and has been known to be false for over 2 years.

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https://publichealth.jhu.edu/2022/covid-and-the-heart-it-spares-no-one

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Until now, people who suffered mild or asymptomatic COVID-19 were thought to have dodged the brunt of the virus’s brutal side effects. But new evidence has revealed that anyone infected with COVID is at higher risk for heart issues—including clots, inflammation, and arrhythmias—a risk that persists even in relatively healthy people long after the illness has passed.

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The major finding was that people with COVID-19 have a higher risk of all sorts of heart problems at one year. That included arrhythmias (irregular heart beats or the heart beating too fast or too slow) and atrial fibrillation (a fast heart rhythm in a particular pattern). We found evidence of an increased risk of stroke, of blood clots in the legs and the lungs, and of heart failure and heart attacks. The increased risk of a broad spectrum of heart problems was evident. 

I went into it thinking that [the risk] was going to be most pronounced and evident in people who smoked a lot or had diabetes, heart disease, kidney disease, or some [other] risk factors. What we found is that even in people who did not have any heart problems start with, were athletic, did not have a high BMI, were not obese, did not smoke, did not have kidney disease or diabetes—even in people who were previously healthy and had no risk factors or problems with the heart—COVID-19 affected them in such a way that manifested the higher risk of heart problems than people who did not get COVID-19.

Anyone who was infected with COVID-19 has a higher risk of CVD than someone that was not infected with COVID-19.

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5 hours ago, OpenMindedSceptic said:

You get called on the Met investigation, and you shut and switch topics.

You get called on a 19:1 ratio, and you shut and switch topics.

You give a link of a body builder that dies from unknown causes with no mention of COVID or a vaccine.  It's time again for you to shut up and switch topics.

Gish Gallop.

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10 hours ago, Golden Duck said:

You get called on the Met investigation, and you shut and switch topics.

You get called on a 19:1 ratio, and you shut and switch topics.

You give a link of a body builder that dies from unknown causes with no mention of COVID or a vaccine.  It's time again for you to shut up and switch topics.

Gish Gallop.

It just lulls you into your cling on trench.

It will not being before every jab supporting, covid fearful, anti-science, pharma supporter will have egg on their face.

Keep digging and cling on.

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2 hours ago, OpenMindedSceptic said:

It just lulls you into your cling on trench.

It will not being before every jab supporting, covid fearful, anti-science, pharma supporter will have egg on their face.

Keep digging and cling on.

If your trying a right-a-dope disscussion, you eventually have to make a valud point.  You're doing it wrong.

We've only seen you with BS on your lips. If you keep spreading the fertiliser, it has to be dug in.  That's what you do.  Unfortunately, it's wasted effort because what ever you've spread has produced nothing.

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7 hours ago, Golden Duck said:

If your trying a right-a-dope disscussion, you eventually have to make a valud point.  You're doing it wrong.

We've only seen you with BS on your lips. If you keep spreading the fertiliser, it has to be dug in.  That's what you do.  Unfortunately, it's wasted effort because what ever you've spread has produced nothing.

We know the type of cling on they are - the type that decent toilet paper removes.

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10 hours ago, Golden Duck said:

If your trying a right-a-dope disscussion, you eventually have to make a valud point.  You're doing it wrong.

We've only seen you with BS on your lips. If you keep spreading the fertiliser, it has to be dug in.  That's what you do.  Unfortunately, it's wasted effort because what ever you've spread has produced nothing.

Really?

I am sure that this plays out very well indeed.

Keep clinging on,,please. It's fun. Oh, it's funny too.

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15 minutes ago, OpenMindedSceptic said:

Really?

I am sure that this plays out very well indeed.

Keep clinging on,,please. It's fun. Oh, it's funny too.

It's fun for you to spread your Met investigation fairy tale.

Enjoy.

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9 hours ago, Golden Duck said:

It's fun for you to spread your Met investigation fairy tale.

Enjoy.

Fairy tales within the fairy tale that covid is a serious virus that required lockdowns and jabs. 

The lie called covid will be exposed to the point it will be common knowledge there was global over reaction. 

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37 minutes ago, OpenMindedSceptic said:

Fairy tales within the fairy tale that covid is a serious virus that required lockdowns and jabs. 

The lie called covid will be exposed to the point it will be common knowledge there was global over reaction. 

Still talking and saying nothing.

Give us more details on the Met investigation you assured us ead under way.

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Numerous studies have shown COVID-19 to be a dangerous disease. There are those that lie and claim that it is not dangerous. But the overwhelming evidence shows that they are ignorant liars.

Over 6 million are dead in the world.

But what about those that did not die. What is happening to them?

It has been established in this thread that for over 2 years it has been known that COVID-19 damages internal organs.

  • kidneys
  • heart
  • vascular system
  • intestines
  • lungs
  • brain
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https://www.health.harvard.edu/blog/what-is-covid-19-brain-fog-and-how-can-you-clear-it-2021030822076
 

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How COVID-19 affects the brain

There are many ways that COVID-19 can damage the brain. As I described in a previous blog post, some can be devastating, such as encephalitis, strokes, and lack of oxygen to the brain. But other effects may be more subtle, such as the persistent impairment in sustained attention noted by Chinese researchers.

In addition to direct effects on the brain, COVID-19 can also have long-term effects on other organ systems. So-called long haulers can have other lingering symptoms including fatigue, body aches, inability to exercise, headache, and difficulty sleeping. Some of these problems may be due to permanent damage to their lungs, heart, kidneys, or other organs. Damage to these organs — or even just the symptoms by themselves — can impair thinking and memory and cause brain fog. For example, how can you think clearly if you’re feeling fatigued and your body is aching? How can you concentrate if you were up half the night and awoke with a headache?

 

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What we do see is that those claiming that COVID-19 is no big deal never express anything but their on ignorance on the matter.

The reality is that medical science is working on determining the full extent of the disease and what injuries are going to be permanent scars on our society.

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Here is some good news on the lung issue. This is an article about a year old.

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Pulmonary Parenchymal Changes in COVID-19 Survivors

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In this study to examine the lung parenchyma of COVID-19 survivors, we did not find distinct postacute histopathologic changes to suggest permanent pulmonary damage. These results are reassuring for COVID-19 survivors who recover and become asymptomatic.

The article suggests that if you recover and lose symptoms of COVID-19 then you are likely to be fine as far as the lungs are concerned.

https://www.medicinenet.com/script/main/art.asp?articlekey=263809

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"This research provided us with the rare opportunity to study the asymptomatic survivors of COVID-19 and make observations to help us answer this question," he said in a Loyola news release.

Autopsies of deceased COVID-19 patients and studies of patients with end-stage lung disease from COVID-19 have found a range of serious lung problems, the researchers noted.

"Further research is still needed on why some patients recover completely, and others don't. Our study shows that if you contract COVID-19 and then completely recover clinically and on imaging, your lung tissues are also likely to have completely healed as well, without permanent damage," Abdelsattar said.

 

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028000/

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Relationship between Lung and Brain Injury in COVID-19 Patients: A Hyperpolarized 129Xe-MRI-based 8-Month Follow-Up

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At present, there is an increased awareness of multiorgan involvement in patients with coronavirus disease (COVID-19) [1,2,3]. Recent studies have shown that a considerable proportion (22–56% across different severity scales) of patients had a pulmonary diffusion abnormality 6 months after the onset of symptoms [4]. Research on persistent symptoms in the brain has shown that neurological symptoms are observed in 36.4% of patients, and are more common in severe cases (45.5%) [3]. These symptoms, including fatigue, muscle weakness, sleep difficulties and smell disorders, are clinical manifestations of neuronal damage caused by a decreased oxygen supply to the brain [5,6,7,8].

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Although the patients’ lung structure returned to normal after approximately 12 months of recovery, the gas–blood exchange function did not fully recover.

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GMV in the increased brain regions in patients with COVID-19 had a strong positive correlation with the lung gas–blood exchange time, suggesting that the increased GMV may have resulted from brain edema caused by persistent hypoxia.

In short the researchers saw that in this initial study, the lungs looked normal but were not working normal and this has led to swelling in the brain which they believe is due to a lack of oxygen reaching the brain.

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https://medicine.yale.edu/news-article/how-effects-on-the-brain-can-produce-long-covid/

 

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COVID-19 may be primarily a respiratory illness, but its reach extends far beyond the lungs. Since the pandemic’s onset, it has become clear to neurologists that the pervasive disease can impact even our most precious organ—the brain. T

 

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Long COVID may result from persistent neuroinflammation triggered during the acute infection, or from other kinds of changes related to autoimmunity. But there is currently a lack of clear evidence supporting either hypothesis. Because long COVID presents in a wide variety of ways, it will take many different specialists working together to understand its pathophysiology. “Our paper was partly trying to draw attention to this topic and galvanize more research investigation,” says Spudich.

 

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  • 2 weeks later...

Another report out on the long term dangers of COVID-19. What has been suspected or over 2 years is unfortunately looking to be correct.

https://www.medscape.com/viewarticle/973598

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González stressed that studies have shown that there are more than 50 long-term effects of COVID-19, the most prevalent being fatigue (58%), headache (44%), attention disorders (27%), and hair loss (25%).

As with most issues the most common are not the worst issues.

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"For example, it has been shown that dyspnea, hypoxia, fatigue, 'ground-glass' opacities, and pulmonary fibrosis are due to damage to the lung parenchyma [primarily] mediated by the virus and secondarily due to immunological microvascular damage. On the other hand, at a cardiovascular level, up to 20 cardiovascular conditions can occur 1 year after overcoming COVID-19. This allows us to foresee that these patients will be a significant demand on health systems in the coming years."

It's the long term issues that are going to be the main trouble with this disease.

The article also points out the benefits of exercise when dealing with long COVID.

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In the context of COVID-19, Martínez explained this positive impact "taking into account that SARS-CoV-2 affects the angiotensin-converting enzyme-2 receptor, and this in turn involves the appearance of fibrosis, inflammation, vasoconstriction, reduced neurogenesis, and cardiovascular damage. This activation of a series of vascular signaling chains that occurs with exercise makes it possible to counteract a good number of the symptoms of the post-COVID-19 syndrome, acting in a certain sense like a polypill."

 

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