+Grim Reaper 6 Posted March 23 #1 Share Posted March 23 Quote Although autism is a common neurodevelopmental disorder, the multiple factors behind its onset are still not fully understood. Animal models of idiopathic autism, especially mice, are often used to help researchers understand the complicated mechanisms behind the disorder, with BTBR/J being the most commonly used mouse model in the world. Now, an international research collaboration made new discoveries regarding autism onset in mouse models. The researchers included Kobe University’s Professor Toru Takumi and Researcher Chia-wen Lin et al. In their detailed series of experiments and analyses of BTBR/J mice and the other subspecies BTBR/R, they revealed that endogenous retrovirus activation increases a fetus’s susceptibility to autism. They also discovered that BTBR/R exhibits autistic-like behaviors without reduced learning ability, making it a more accurate model of autism than the widely-used BTBR/J model. It is hoped that further research will contribute towards better classification of autism types, as well as the creation of new treatment strategies for neurodevelopmental disorders. https://scitechdaily.com/does-ancient-virus-genome-drive-autism/ 3 Top Link to comment Share on other sites More sharing options...
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