Breakthrough Research Supercharges Naloxone’s Power Against Deadly Opioids

[Grim Reaper 6]

The ongoing opioid crisis in the U.S. claims tens of thousands of lives annually. Naloxone, known by its brand name Narcan, has been instrumental in saving numerous lives by reversing opioid overdoses. However, the emergence of new, more potent opioids is making it increasingly challenging for first responders to revive individuals who overdose.

Now, researchers have found an approach that could extend naloxone’s lifesaving power, even in the face of ever-more-dangerous opioids. A team of researchers from Washington University School of Medicine in St. Louis, Stanford University and the University of Floridahave identified potential drugs that make naloxone more potent and longer lasting, capable of reversing the effects of opioids in mice at low doses without worsening withdrawal symptoms. The study is published July 3 in Nature..

https://scitechdaily.com/breakthrough-research-supercharges-naloxones-power-against-deadly-opioids/.

A µ-opioid receptor modulator that works cooperatively with naloxone:  https://www.nature.com/articles/s41586-024-07587-7

[Ell]

Quote

"The first thing we do, let's kill all the physicians". (Paraphrased)

 William Shakespeare's Henry VI, Part 2, Act IV, Scene 2.

 

Edited August 5 by Ell

[Occupational Hubris]

1 hour ago, Ell said:

 

"No."

-Hamlet. Act 3. Scene 3. Line 92

Edited August 5 by Occupational Hubris

[Grim Reaper 6]

8 hours ago, Ell said:

 

You guys are crazy and you also have a sick sense of humor, but I like it!

7 hours ago, Occupational Hubris said:

"No."

-Hamlet. Act 3. Scene 3. Line 92