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Science & Technology

Scientists create first ever lab-grown limb

By T.K. Randall
June 4, 2015 · Comment icon 15 comments

Lab-grown limbs and organs could remove the need for donors. Image Credit: NCI/NIH
The possibility of growing replacement limbs for amputees is now one step closer to becoming a reality.
A great deal of progress has been made in recent years in the development of artificial legs, bionic hands and even brain-control interfaces that can enable someone to move a robotic arm using nothing more than the power of their own mind.

The ultimate solution however, one with the potential to completely restore an amputee's missing limb, is to use their own cells to grow an entirely new one that will function exactly as the original did.

While this might sound like something out of a science fiction movie, scientists recently announced that they'd succeeded for the first time in growing an actual rat limb in a laboratory.

Grown by researchers at Massachusetts General Hospital, the rat limb not only looks the part but also contains functioning veins and muscle tissue as well.
"The composite nature of our limbs makes building a functional biological replacement particularly challenging," said senior author Dr Harald Ott.

"Limbs contain muscles, bone, cartilage, blood vessels, tendons, ligaments and nerves - each of which has to be rebuilt and requires a specific supporting structure called the matrix."

Using a patient's own genetic material to grow replacement body parts has long been one of the holy grails of modern medicine as not only does it completely remove the need for donors but it also avoids both the risk of rejection and a future reliance on immunosuppressant drugs.

It is still likely to take quite a few more years however for the technique to be perfected.

Source: Yahoo! News | Comments (15)




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Recent comments on this story
Comment icon #6 Posted by Cesadelo 9 years ago
It's astonishing, yet I have to say that this already happened around 20-25 years ago.
Comment icon #7 Posted by paperdyer 9 years ago
That's great news! My son-in-law has a deformed right hand that didn't develop. This could help him. At least if the recipient's DNA is used, we don't have to worry about what happened to Dr. Connor in Spider-Man (The Lizard)
Comment icon #8 Posted by Dark_Grey 9 years ago
It will be interesting down the road when some people request robotic limbs and others want the certified organic© limbs. Eventually, it will be all out war between the "normies" and the cyborgs. (SPOILER: The cyborgs win)
Comment icon #9 Posted by BeastieRunner 9 years ago
This is pretty cool. I have a friend with no limbs and she actually pointed this story out on my Facebook. If it did become viable, I don't see her using it, though.
Comment icon #10 Posted by Imaginarynumber1 9 years ago
Finally!!! Now They can grow me a gorilla-cyborg body!
Comment icon #11 Posted by chiphead 9 years ago
So is the regrown limb actually attached to the rat; as in, the rat grew the limb back? Or is it just grown in a petre dish and there is still the challenge of attaching it to regain full functionality?
Comment icon #12 Posted by FissionChip 9 years ago
It seems it was done both in vitro and in vivo, so they may in fact have reconnected the limb, but the abstract is too technical for me to understand with any certainty. Other scientists have performed hand transplants though that have been successful and this new science will make those transplants even easier.
Comment icon #13 Posted by Zalmoxis 9 years ago
What I see is that regenerating body parts will one day become ingrained in our DNA once scientists perfect it in the laboratory.
Comment icon #14 Posted by Myles 9 years ago
Pretty cool stuff. I wonder how long it will be till you can replace limbs that are defective (arthritis ect..)
Comment icon #15 Posted by TheGreatBeliever 9 years ago
They say in the near future we could grow back a limb..


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