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Science & Technology

Scientists create mice from artificial eggs

By T.K. Randall
October 17, 2016 · Comment icon 9 comments

It is now possible to create fertilizable eggs in a laboratory. Image Credit: sxc.hu
Japanese scientists have succeeded in creating female mouse eggs using cells from the animals' tails.
In what has been described as a 'remarkable' breakthrough, researchers from Kyushu University not only managed to create viable eggs in a laboratory but even succeeded in having a female mouse bring them to term.

The technique involved taking tissue cells from the tail of a mouse and then reprogramming them as stem cells to turn them in to eggs. These were then fertilized and implanted in to a female mouse.

The resulting pups turned out to be perfectly healthy despite their unique conception.

"This is the first time a functional egg has been produced from stem cells in culture which gives us some clue to human egg production from stem cells," said Professor Katsuhiko Hayashi.
"We need to now carefully look at the quality of mouse artificial eggs. This kind of quality check will contribute to an application to humans in future."

In the future this technique could prove extremely beneficial to women suffering from infertility.

"This is the first report of anyone being able to develop fully mature and fertilizable eggs in a laboratory setting right through from the earliest stages of egg development," said clinical reproductive scientist Professor Richard Anderson.

"Although we are a long way from making artificial eggs for women at the moment, this study also provides us with a basis for experimental models to explore how eggs develop from other species, including in women."

Source: Telegraph | Comments (9)

Recent comments on this story
Comment icon #1 Posted by Parsec 7 years ago
Like for the news about mice created with skin cells, it's at the same time fascinating and disturbing.† † Well, at least now we can remove from the "possible doomsday scenarios" †list the one where humankind becomes sterile, like in Children of Men.† † On the other hand, †now "the powers that be" can sterilise everybody and allow only who they deem worth to bring forth a pregnancy.†
Comment icon #2 Posted by bubblykiss 7 years ago
Well I for one am glad that science is working so diligently to solve our mouse shortage. †
Comment icon #3 Posted by Wickian 7 years ago
Our understanding of how to experiment on mice will grow by leaps and bounds, no doubt.
Comment icon #4 Posted by PersonFromPorlock 7 years ago
Man is God's way of creating the perfect mouse.
Comment icon #5 Posted by danielost 7 years ago
any cell can be used to clone or produce eggs since they all hold the info to create a new body.
Comment icon #6 Posted by paperdyer 7 years ago
Don't worry bubbly, they'll work on the rabbit shortage next.
Comment icon #7 Posted by paperdyer 7 years ago
"Gee Brain, what are we doing tonight?"† "The same thing we do every night Pinky, try to take over the world!"
Comment icon #8 Posted by White Unicorn 7 years ago
I think it's a great break through experiment, it has many implications for the future. Man is God's way of creating the perfect mouse. LOL that was a good one! Building a better mouse will lead to humans as well. More than one way to skin a cat, comes to my mind. Nature does things by the easiest method to create new offspring. When it fails, man steps in to do it in other more complicated methods, now they are learning just one skin cell can be altered to use in many ways. So there are many more ways to skin the proverbial cat then scientists first thought.
Comment icon #9 Posted by UFOwatcher 7 years ago
But can we use mice to produce eggs and bacon?

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